Pediatric Allergy and Immunology is a vital subject to be learnt to focus on factors identified with child’s immune system. Many children who have mild adverse reactions to penicillins; such as maculopapular rash; hives; or gastrointestinal symptoms; are not hypersensitive and can securely get this class of anti-infection agents in the future. Anaphylaxis is a serious allergic reaction that is quick in onset and may cause death. Food allergy affects around 6 to 8 percent of kids under five years old. Oral immunotherapy for nourishments is an investigational treatment for food allergies that can prompt brief desensitization to a food; however the capacity of oral immunotherapy to initiate permanent tolerance to the food is less certain. Ecological and food allergies in children occur when the children’s immune system responds to ordinary innocuous substances present in the environment.